RTA10
Laboratory-grade research compound, prepared and packaged under controlled conditions. Not for human or animal consumption. For in vitro research use only.
Related compounds
Research Material Overview
Retatrutide (developmental designation LY3437943) is a synthetic peptide analog engineered as a triple receptor agonist at the glucagon (GCGR), glucose-dependent insulinotropic polypeptide (GIPR), and glucagon-like peptide-1 (GLP-1R) receptors. In preclinical and early-phase research models, simultaneous activation of these three increin-related pathways has been studied in relation to energy balance, glucose homeostasis, and lipid metabolism. CloudComps supplies retatrutide as a lyophilized research material for in vitro and laboratory investigation only.
Physical Description
Supplied as a white to off-white lyophilized solid in a sealed, sterile-capped glass vial. The lyophilized cake is hygroscopic and should be handled under conditions that minimize moisture exposure. Prior to in vitro use, the material is reconstituted with an appropriate sterile, research-grade solvent as described in the accompanying documentation.
Molecular Information
- Appearance
- White to off-white lyophilized powder
- Molecular formula
- C221H342N51O68
- Molecular weight
- ~4732 g/mol
- CAS number
- 2381089-83-2
- Classification
- 41-amino-acid synthetic peptide; triple GIP/GLP-1/glucagon receptor agonist
Purity & Testing Information
Reported purity of ≥ 99% is determined by reversed-phase high-performance liquid chromatography (RP-HPLC) under the analytical conditions specified on the accompanying Certificate of Analysis. Each lot is accompanied by lot-specific analytical documentation including the chromatographic method and detection conditions. A purity value reflects the proportion of the analyzed material attributed to the target peptide under the stated method and does not, by itself, confirm identity or exclude every possible impurity.
Available Documentation
- Lot-specific Certificate of Analysis (COA)
- RP-HPLC chromatogram with purity calculation
- Mass spectrometry (LC-MS) data
- Solubility and reconstitution guidance
- Chain of custody and storage documentation
Storage Information
Store the lyophilized material at -20°C in the original sealed vial, protected from light and moisture. After reconstitution, aliquot and store at 2-8°C for short-term use or at -20°C for longer storage. Avoid repeated freeze-thaw cycles. Stability under specific experimental conditions should be validated by the researcher.
Frequently Asked Questions
What receptor profile distinguishes retatrutide from dual agonists?
Retatrutide is characterized as a triple agonist of the glucagon, GIP, and GLP-1 receptors, whereas dual agonists target two of these pathways. The simultaneous engagement of three increin-related receptors is the basis for its investigation in metabolic research models.
Is this material suitable for clinical or human use?
No. Retatrutide supplied by CloudComps is intended exclusively for in vitro laboratory and scientific research. It is not for human or veterinary consumption or clinical application.
How should reconstitution be approached?
Reconstitution should be performed using an appropriate sterile, research-grade solvent under aseptic conditions. Specific guidance is provided with the accompanying documentation; researchers should verify suitability for their intended in vitro application.
Related Research Resources
Research-Use Disclaimer
Retatrutide is intended exclusively for in vitro laboratory and scientific research purposes. It is not for human or veterinary consumption, clinical use, or diagnostic application. Researchers should review the complete analytical documentation, handle the material in accordance with appropriate laboratory practices, and comply with all applicable regulations. Statements regarding receptor activity or research interest refer to preclinical study contexts and do not imply suitability for any particular application.


